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ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as game-changers across the cardiovascular–kidney–metabolic (CKM) spectrum: overweight/obesity, type 2 diabetes mellitus…
SummaryBackgroundGlobally, the burden of chronic kidney disease and ensuing need for kidney replacement therapy (KRT)—dialysis or kidney transplantation—are increasing. Despite the mortality benefit…
Published date
August 2025
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Zambeli-Ljepović, A., Tungsanga, S., Ghimire, A., Bello, ak., Okpechi, IG., Siyoum, MT., Mushi, FA., Asiimwe, F., Bagasha, P., Okungu, V., Bertozzi, SM., Hoffmann, TJ., Thomson, D., Muller, E., Scott, JW., Syed, S., Ascher, N., Stock, P., Rose, J.
AbstractThe burden of chronic kidney disease (CKD) and its risk factors are projected to rise in parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category G3–G5 may…
Published date
July 2024
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Chesnaye, NC., Ortiz, A., Zoccali, C., Stel, VS., Jager, KJ.
The current kidney care model-focused on late-stage disease and in-center hemodialysis-is unsustainable, because of costs, environmental burden, poor outcomes, and reduced quality of life.The 78th…
Published date
March 2026
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Vanholder, R., Abdellatif, D., Dos Santos Jr, ACS., Correa-Rotter, R., Gopalakrishnan, N., Wang, B., Roumeliotis, S., Balducci, A., Haris, A., Yadla, M., Hsiao, L.
BMJ News article by Jacqui Wise, with comment from CSH's CEO, Rachel Stancliffe.There is so much evidence now about the relationship between climate change and health. Here is another way in which…
Despite the availability of kidney replacement therapy (KRT), chronic kidney disease (CKD) is among the fastest increasing global causes of premature death. Longer life expectancy and population aging…
Sex (biologically determined) and gender (socially constructed) modulate manifestations and prognosis of a vast number of diseases, including cardiovascular disease (CVD) and chronic kidney disease…
Published date
February 2024
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Balafa, O., Fernandez-Fernandez, B., Ortiz, A., Dounousi, E., Ekart, R., Ferro, CJ., Mark, PB., Valdivielso, JM., Del Vecchio, L., Mallamaci, F.
Diabetes is the most common cause of chronic kidney disease (CKD), a condition found in 850 million persons and projected to become the fifth global cause of death by 2040. Research is needed that…
AbstractUromodulin is a kidney-specific glycoprotein which is uniquely synthesized by the epithelial cells lining the thick ascending limb and early distal convoluted tubule. Among multiple roles in…
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Karagiannidis, AG., Theodorakopoulou, MP., Iatridi, F., Ortiz, A., Sarafidis, P
Hemodialysis, hemodiafiltration, and peritoneal dialysis are among the most resource-intensive medical therapies, owing to their high energy and water consumption, heavy reliance on disposable…
Published date
March 2026
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Katherine A. Barraclough, Nathan Berman-Parks, Vivekanand Jha , Giorgina B. Piccoli, Caroline Stigant , Ben Talbot, Faissal Tarrass, Michael Cheung , Jennifer M. King , Morgan E. Grams, Michel Jadoul, Jennifer E. F
